Prescription Drugs

Certain toxins and drug overdoses can be removed via extracorporeal therapy

Molecules <40KDa
Protein binding <80%

Ethylene glycol
Methanol
Ethanol
Phenobarbital
Caffeine
Lithium
Salicylates
Betablockers
Theophyline
Meprobamate
Metformin
Cyclophosphamide
Baclofen

Molecular weight <40KDa
Volume of distribution > 0.5L/kg
Protein binding >80%

Enrofloxacin
Amatoxins
Amitriptyline
Vincristine
Ibuprofen

Therapeutic plasma exchange

Molecular weight >40KDa
Protein binding >80%
Volume of distribution < 0.5 L/Kg
PB<80%+MW>40KDa+Vd <1 L/Kg

Detemir insulin
Envenemation
Ibuprofen
Mushroom
Onsior
Vincristine

Hemoperfusion

Hemodialysis & hemodiafiltration